2024

Morstein J, Bowcut V, Fernando M, Yang Y, Zhu L, Jenkins ML, Evans JT, Guiley KZ, Peacock DM, Krahnke S, Lin Z, Taran KA, Huang BJ, Stephen AG, Burke JE, Lightstone FC, Shokat KM. Targeting Ras-, Rho-, and Rab-Family GTPases via a Conserved Cryptic Pocket. Cell. 2024 Sep 6:S0092-8674(24)00908-5. doi: 10.1016/j.cell.2024.08.017. PMID: 39255801. Online ahead of print.

Levinson A, Shannon K, Huang BJ. Targeting Hyperactive Ras Signaling in Pediatric Cancer. Cold Spring Harb Perspect Med. 2024 Jul 15:a041572. doi: 10.1101/cshperspect.a041572. PMID: 39009442.

Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek JL, Rusch M, Rahbarinia D, Foy S, Huang BJ, Walsh MP, Kumar P, Liu Y, Ma X, Wang L, Rubnitz JE, Pounds S, Klco JM. A new genomic framework to categorize pediatric acute myeloid leukemia. Nat Genetics. 2024 Feb;56(2):281-293. doi: 10.1038/s41588-023-01640-3. PMID: 38212634.

2023

Mandal K, Wicaksono G, Yu C, Adams JJ, Hoopman MR, Temple WC, Patino Escobar B, Gorelik M, Ihling CH, Nix MA, Naik A, Ramos E, Kasap C, Steri V, Camara Serrano J, Salangsang F, Phojanakong P, McMillan M, Gavallos V, Leavitt AD, Sinz A, Huang BJ, Stieglitz E, Smith CC, Moritz RL, Sidhu SS, Huang L, Wiita AP. Structural surfaceomics reveals an AML-specific conformation of Integrin-β2 as an immunotherapeutic target. Nat Cancer. 2023 Nov;4(11):1592-1609. doi: 10.1038/s43018-023-00652-6. PMID: 37904046.

Chen P-Y*, Huang BJ*, Harris M, Boone C, Wang W, Carias H, Mesiona B, Mavrici D, Kohler A, Bollag G, Zhang C, Zhang Y, Shannon K. Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation. JCI Insight. 2023 Sep 8;8(17):e168445. doi: 10.1172/jci.insight.168445. PMID: 37681415. [*contributed equally]

Farrar JE, Smith JL, Othus M, Huang BJ, Wang Y-C, Ries RE, Hylkema T, Pogosova-Agadjanyan EL, Challa S, Leonti AR, Shaw TI, Triche TJ, Gamis AS, Aplenc R, Kolb EA, Ma X, Stirewalt DL, Alonzo TA, Meshinchi S. Long Non-Coding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia. J Clin Oncol. 2023 Jun 1;41(16):2949-2962. doi: 10.1200/JCO.22.01114. PMID: 36795987.

2022 (Huang Lab Est.)

Le Q, Hadland B, Smith JL, Leonti A, Huang BJ, Ries R, Hylkema TA, Castro S, Tang TT, McKay CN, Perkins L, Pardo L, Sarthy J, Beckman AK, Williams R, Idemmili R, Furlan S, Ishida T, Call L, Srivastava S, Loeb AM, Milano F, Imren S, Morris SM, Pakiam F, Olson JM, Loken MR, Eidenschink Brodersen L, Riddell SR, Tarlock K, Bernstein ID, Loeb KR, Meshinchi S. CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target. J Clin Invest. 2022 Sep 22:e157101. doi: 10.1172/JCI157101. PMID: 36136600.

Huang BJ, Smith JL, Farrar JE, Wang YC, Umeda M, Ries RE, Leonti AR, Crowgey E, Furlan SN, Tarlock K, Armendariz M, Liu Y, Shaw TI, Wei L, Gerbing R, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Rubnitz J, Ma J, Klco JM, Ma X, Alonzo TA, Triche T, Meshinchi S. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nat Commun. 2022 Sep 19;13(1):5487. doi: 10.1038/s41467-022-33244-6. PMID: 36123353.

Umeda M, Ma J, Huang BJ, Hagiwara K, Westover T, Abdelhamed S, Barajas JM, Thomas ME, Walsh MP, Song G, Miller J, Hiltenbrand R, Liu Y, Chen X, Foy X, Iacobucci I, Kleist AB, Ries RE, Wu H, Rusch M, Alonzo TA, Maciaszek JL, Inaba H, Wu G, Valentine V, Valentine M, Liu YC, Mullighan CG, Pounds S, Babu MM, Zhang J, Rubnitz JE, Meshinchi S, Ma X, Klco JM. Integrated genomic analysis identifies UBTF tandem duplications as a recurrent lesion in pediatric acute myeloid leukemia. Blood Cancer Discov. 2022 Feb 16. doi: 10.1158/2643-3230.BCD-21-0160. PMID: 35176137.

2021

Huang BJ, Smith JL, Shaw TI, Furlan SN, Ries RE, Leonti AR, Crowgey EL, Wei L, Farrar JE, Trich T, Ma X, Le Q, Meshinchi S. Integrated transcriptomics and proteomics identifies therapeutic targets in pediatric acute myeloid leukemia. Blood. 2021 Nov 5;138(S1):1296. doi: 10.1182/blood-2021-153970. [Manuscript in Preparation]

Huang BJ, Smith JL, Wang YC, Taghizadeh K, Leonti AR, Ries RE, Liu Y, Kolekar P, Tarlock K, Gerbing R, Crowgey EL, Furlan SN, Shaw TI, Hagiwara K, Wei L, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche T, Alonzo TA, Ma X, Meshinchi S. CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes. Blood Adv. 2021 Dec 14;5(23):4963-4968. doi: 10.1182/bloodadvances.2021004965. PMID: 34547772.

Remsberg J, Suciu R, Zambetti N, Hanigan T, Firestone A, Inguva A, Long A, Ngo N, Lum K, Henry C, Richardson S, Predovic M, Huang BJ, Howell A, Niphakis M, Shannon K, Cravatt B. ABHD17 enzymes regulate dynamic plasma membrane palmitoylation and N-Ras-dependent cancer growth. Nat Chem Biol. 2021 Apr 29. doi: 10.1038/s41589-021-00785-8. PMID: 33927411.

Peretz C, McGary L, Kumar T, Jackson H, Jacob J, Durruthy-Durruthy R, Levis M, Perl A, Huang BJ, Smith C. Single cell DNA sequencing reveals complex mechanisms of resistance to quizartinib. Blood Adv. 2021 Mar 9;5(5):1437-1441. doi: 10.1182/bloodadvances.2020003398. PMID: 33666651.

2020

Huang BJ, Wang X, Harris M, Wandler A, Hwang E, Burgess MR, Li Q, Severson P, Powell B, Kolb EA, Meshinchi S, Taylor BS, Bollag G, Shannon K. Co-Targeting BET bromodomain proteins and aberrant signaling in AML. Blood. 2020 Nov 5;136(S1):5-6. doi: 10.1182/blood-2020-142921. [Manuscript in Review]

Zambetti NA, Firestone AJ, Remsberg JR, Huang BJ, Wong JC, Long AM, Predovic M, Suciu RM, Inguva A, Kogan SC, Haigis KM, Cravatt BF, Shannon K. Genetic disruption of palmitoylation abrogates hematopoietic transformation by NrasG12D in vivo. Blood. 2020 May 14;135(20):1772-1782. doi: 10.1182/blood.2019003530. PMID: 32219446.

Meyer LK, Huang BJ, Delgado-Martin C, Roy R, Hechmer A, Wandler AM, Vincent TL, Olshen A, Wood BL, Horton TM, Shannon KM, Teachey DT, Hermiston ML. Glucocorticoids paradoxically facilitate steroid resistance in T-cell acute lymphoblastic leukemias. J Clin Invest. 2020 Feb 3;130(2):863-876. doi: 10.1172/JCI130189. PMID: 31687977.

2019 and earlier

Huang BJ, Wandler A, Meyer L, Dail M, Daemen A, Sampath D, Li Q, Wang X, Wong JC, Nakitandwe J, Downing JR, Zhang J, Taylor B, Shannon K. Convergent Genetic Aberrations in Murine and Human T Lineage Acute Lymphoblastic Leukemias. PLoS Genet. 2019 Jun 14;15(6):e1008168. doi: 10.1371/journal.pgen.1008168. PMID: 31199785.

Burgess MR, Hwang E, Mroue R, Bielski CM, Wandler AM, Huang BJ, Firestone AJ, Young A, LaCap J, Crocker L, Asthana S, Davis EM, Xu J, Akagi K, Le Beau MM, Li Q, Stokoe D, Sampath D, Taylor BS, Evangelista M, Shannon K. KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer. Cell. 2017 Feb 23;168(5):817-829.e15. doi: 10.1016/j.cell.2017.01.020. PMID: 28215705.

2024

Morstein J, Bowcut V, Fernando M, Yang Y, Zhu L, Jenkins ML, Evans JT, Guiley KZ, Peacock DM, Krahnke S, Lin Z, Taran KA, Huang BJ, Stephen AG, Burke JE, Lightstone FC, Shokat KM. Targeting Ras-, Rho-, and Rab-Family GTPases via a Conserved Cryptic Pocket. Cell. 2024 Sep 6:S0092-8674(24)00908-5. doi: 10.1016/j.cell.2024.08.017. PMID: 39255801. Online ahead of print.

Levinson A, Shannon K, Huang BJ. Targeting Hyperactive Ras Signaling in Pediatric Cancer. Cold Spring Harb Perspect Med. 2024 Jul 15:a041572. doi: 10.1101/cshperspect.a041572. PMID: 39009442.

Wong JC, Weinfurtner KM, Westover T, Kim J, Lebish EJ, Del Pilar Alzamora P, Huang BJ, Walsh M, Abdelhamed S, Ma J, Klco JM, Shannon K. 5G2 Mutant Mice Model Loss of a Commonly Deleted Segment of Chromosome 7q22 in Myeloid Malignancies. Leukemia. 2024 May;38(5):1182-1186. doi: 10.1038/s41375-024-02205-x. PMID: 38443608.

Tarlock T, Gerbing RB, Ries RE, Smith JL, Leonti AR, Huang BJ, Kirkey DC, Robinson L, Peplinski JH, Lange B, Cooper TM, Gamis AS, Kolb EA, Aplenc R, Pollard JA, Meshinchi S. Prognostic Impact of Co-occurring Mutations in FLT3-ITD Pediatric Acute Myeloid Leukemia. Blood Adv. 2024 May 14;8(9):2094-2103. doi: 10.1182/bloodadvances.2023011980. PMID: 38295280.

Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek JL, Rusch M, Rahbarinia D, Foy S, Huang BJ, Walsh MP, Kumar P, Liu Y, Ma X, Wang L, Rubnitz JE, Pounds S, Klco JM. A new genomic framework to categorize pediatric acute myeloid leukemia. Nat Genetics. 2024 Feb;56(2):281-293. doi: 10.1038/s41588-023-01640-3. PMID: 38212634.

Perkins IU, Tan SY, McCalmont TH, Chou PM, Mully TW, Gerami P, Pomerantz JH, Reyes-Mugica M, Balkin DM, Kruse LL, Huang BJ, Reichek JL, Gangopadhyay N, Chiosea S, Green JR, Chamlin SL, Frieden IJ, Bastian BC, Yeh I. Melanoma in infants, caused by a gene fusion involving the anaplastic lymphoma kinase ALK. Pigment Cell Melanoma Res. 2024 Jan;37(1):6-14. doi: 10.1111/pcmr.13115. PMID: 37475109.

2023

Meyer LK, Huang I, Huang BJ, Chung JH, Pawar A, Hermiston ML, Loh ML, Ohgami RS, Ruiz-Cordero R, Bhargava P, Marinoff AE. Hemophagocytic lymphohistiocytosis and clonally related T-cell malignancies in a pediatric patient. Pediatr Blood Cancer. 2023 Dec;70(12):e30677. doi: 10.1002/pbc.30677. PMID: 37702960.

Temple WC, Nix MA, Naik A, Izgutdina A, Huang BJ, Wicaksono G, Phojanakong P, Camara Serrano JA, Young EP, Ramos E, Salangsang F, Steri V, Xirenayi S, Hermiston ML, Logan AC, Stieglitz E, Wiita AP. Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies. J Immunother Cancer. 2023 Nov 24;11(11):e006985. doi: 10.1136/jitc-2023-006985. PMID: 38007238.

Mandal K, Wicaksono G, Yu C, Adams JJ, Hoopman MR, Temple WC, Patino Escobar B, Gorelik M, Ihling CH, Nix MA, Naik A, Ramos E, Kasap C, Steri V, Camara Serrano J, Salangsang F, Phojanakong P, McMillan M, Gavallos V, Leavitt AD, Sinz A, Huang BJ, Stieglitz E, Smith CC, Moritz RL, Sidhu SS, Huang L, Wiita AP. Structural surfaceomics reveals an AML-specific conformation of Integrin-β2 as an immunotherapeutic target. Nat Cancer. 2023 Nov;4(11):1592-1609. doi: 10.1038/s43018-023-00652-6. PMID: 37904046.

Chen P-Y*, Huang BJ*, Harris M, Boone C, Wang W, Carias H, Mesiona B, Mavrici D, Kohler A, Bollag G, Zhang C, Zhang Y, Shannon K. Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation. JCI Insight. 2023 Sep 8;8(17):e168445. doi: 10.1172/jci.insight.168445. PMID: 37681415. [*contributed equally]

Levinson AL, Tjoa K, Huang BJ, Meyer LK, Kim M-O, Brady SW, Zhang J, Shannon K, Wandler AM. Opposing Effects of KDM6A and JDP2 on Glucocorticoid Sensitivity in T-ALL. Blood Adv. 2023 Jul 25;7(14):3479-3484. doi.org: 10.1182/bloodadvances.2021006881. PMID: 36897249.

Farrar JE, Smith JL, Othus M, Huang BJ, Wang Y-C, Ries RE, Hylkema T, Pogosova-Agadjanyan EL, Challa S, Leonti AR, Shaw TI, Triche TJ, Gamis AS, Aplenc R, Kolb EA, Ma X, Stirewalt DL, Alonzo TA, Meshinchi S. Long Non-Coding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia. J Clin Oncol. 2023 Jun 1;41(16):2949-2962. doi: 10.1200/JCO.22.01114. PMID: 36795987.

Marinoff A, Aaronson K, Agrawal AK, Braun BS, Golden C, Huang BJ, Michlitsch J, Southworth S, Thrall A, Vo K, Stieglitz E. Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies. Pediatr Blood Cancer. 2023 Apr 10;e30335. doi: 10.1002/pbc.30335. PMID: 37036306.

Liu Y, Klein J, Bajpai R, Dong L, Tran Q, Kolekar P, Smith JL, Ries RE, Huang BJ, Wang J, Alonzo T, Tian L, Mulder HL, Szlachta K, Shaw TI, Ma J, Walsh M, Song G, Westover T, Autre R, Gout A, Wheeler D, Wan S, Wu G, Yang JJ, Evans W, Loh M, Easton J, Klco JM, Meshinchi S, Brown PA, Pruett-Miller SM, Ma X. Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication. Nat Comm. 2023 Apr 5;14(1):1739. doi: 10.1038/s41467-023-37438-4. PMID: 37019972.

Ferrato MH, Marsh AG, Franke K, Huang BJ, Kolb EA, DeRyckere D, Graham DK, Chan-Chandrasekaran S, Crowgey EL. Machine learning classifier approaches for pedicting response to RTK-Type-III inhibitors demonstrates high accuracy using transcriptomic signatures and ex vivo data. Bioinform Adv. 2023 Mar 22;3(1):vbad034. doi: 10.1093/bioadv/vbad034. PMID: 37250111.

2022 (Huang Lab Est.)

Le Q, Hadland B, Smith JL, Leonti A, Huang BJ, Ries R, Hylkema TA, Castro S, Tang TT, McKay CN, Perkins L, Pardo L, Sarthy J, Beckman AK, Williams R, Idemmili R, Furlan S, Ishida T, Call L, Srivastava S, Loeb AM, Milano F, Imren S, Morris SM, Pakiam F, Olson JM, Loken MR, Eidenschink Brodersen L, Riddell SR, Tarlock K, Bernstein ID, Loeb KR, Meshinchi S. CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target. J Clin Invest. 2022 Sep 22:e157101. doi: 10.1172/JCI157101. PMID: 36136600.

Huang BJ, Smith JL, Farrar JE, Wang YC, Umeda M, Ries RE, Leonti AR, Crowgey E, Furlan SN, Tarlock K, Armendariz M, Liu Y, Shaw TI, Wei L, Gerbing R, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Rubnitz J, Ma J, Klco JM, Ma X, Alonzo TA, Triche T, Meshinchi S. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nat Commun. 2022 Sep 19;13(1):5487. doi: 10.1038/s41467-022-33244-6. PMID: 36123353.

Meyer LK, Delgado-Martin C, Sharp PP, Huang BJ, McMinn D, Vincent TL, Ryan T, Horton TM, Wood BL, Teachey DT, Taunton J, Kirk CJ, Hermiston ML. Inhibition of the Sec61 translocon overcomes cytokine-induced glucocorticoid reistance in T-cell acute lymphoblastic leukemia. Br J Haematol. 2022 Apr 17. doi: 10.1111/bjh.18181. PMID: 35434798.

Umeda M, Ma J, Huang BJ, Hagiwara K, Westover T, Abdelhamed S, Barajas JM, Thomas ME, Walsh MP, Song G, Miller J, Hiltenbrand R, Liu Y, Chen X, Foy X, Iacobucci I, Kleist AB, Ries RE, Wu H, Rusch M, Alonzo TA, Maciaszek JL, Inaba H, Wu G, Valentine V, Valentine M, Liu YC, Mullighan CG, Pounds S, Babu MM, Zhang J, Rubnitz JE, Meshinchi S, Ma X, Klco JM. Integrated genomic analysis identifies UBTF tandem duplications as a recurrent lesion in pediatric acute myeloid leukemia. Blood Cancer Discov. 2022 Feb 16. doi: 10.1158/2643-3230.BCD-21-0160. PMID: 35176137.

2021

Huang BJ, Smith JL, Shaw TI, Furlan SN, Ries RE, Leonti AR, Crowgey EL, Wei L, Farrar JE, Trich T, Ma X, Le Q, Meshinchi S. Integrated transcriptomics and proteomics identifies therapeutic targets in pediatric acute myeloid leukemia. Blood. 2021 Nov 5;138(S1):1296. doi: 10.1182/blood-2021-153970. [Manuscript in Preparation]

Huang BJ, Smith JL, Wang YC, Taghizadeh K, Leonti AR, Ries RE, Liu Y, Kolekar P, Tarlock K, Gerbing R, Crowgey EL, Furlan SN, Shaw TI, Hagiwara K, Wei L, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche T, Alonzo TA, Ma X, Meshinchi S. CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes. Blood Adv. 2021 Dec 14;5(23):4963-4968. doi: 10.1182/bloodadvances.2021004965. PMID: 34547772.

Remsberg J, Suciu R, Zambetti N, Hanigan T, Firestone A, Inguva A, Long A, Ngo N, Lum K, Henry C, Richardson S, Predovic M, Huang BJ, Howell A, Niphakis M, Shannon K, Cravatt B. ABHD17 enzymes regulate dynamic plasma membrane palmitoylation and N-Ras-dependent cancer growth. Nat Chem Biol. 2021 Apr 29. doi: 10.1038/s41589-021-00785-8. PMID: 33927411.

Peretz C, McGary L, Kumar T, Jackson H, Jacob J, Durruthy-Durruthy R, Levis M, Perl A, Huang BJ, Smith C. Single cell DNA sequencing reveals complex mechanisms of resistance to quizartinib. Blood Adv. 2021 Mar 9;5(5):1437-1441. doi: 10.1182/bloodadvances.2020003398. PMID: 33666651.

2020

Huang BJ, Wang X, Harris M, Wandler A, Hwang E, Burgess MR, Li Q, Severson P, Powell B, Kolb EA, Meshinchi S, Taylor BS, Bollag G, Shannon K. Co-Targeting BET bromodomain proteins and aberrant signaling in AML. Blood. 2020 Nov 5;136(S1):5-6. doi: 10.1182/blood-2020-142921. [Manuscript in Review]

Pucciarelli D, Angus SP, Huang BJ, Zhang C, Krishnamurthi G, Bandyopadhyay S, Clapp W, Shannon K, Johnson GL, Nakamura JL. Nf1 mutant tumors undergo transcriptome and kinome re-modeling after inhibition of either mTOR or MEK. Mol Cancer Ther. 2020 Aug 26;molcanther.1017.2019. doi: 10.1158/1535-7163.MCT-19-1017. PMID: 32847978.

Zambetti NA, Firestone AJ, Remsberg JR, Huang BJ, Wong JC, Long AM, Predovic M, Suciu RM, Inguva A, Kogan SC, Haigis KM, Cravatt BF, Shannon K. Genetic disruption of palmitoylation abrogates hematopoietic transformation by NrasG12D in vivo. Blood. 2020 May 14;135(20):1772-1782. doi: 10.1182/blood.2019003530. PMID: 32219446.

Wandler AM, Huang BJ, Craig J, Hayes K, Yan H, Meyer LK, Scacchetti A, Monsalve G, Dail M, Li Q, Wong JC, Weinberg O, Hasserjian RP, Kogan SC, Yamamoto K, Sampath D, Nakitandwe J, Downing JR, Zhang J, Aster JC, Taylor BS, and Shannon K. Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia. Leukemia. 2020 Aug;34(8):2025-2037. doi: 10.1038/s41375-020-0748-6. PMID: 32066867.

Meyer LK, Huang BJ, Delgado-Martin C, Roy R, Hechmer A, Wandler AM, Vincent TL, Olshen A, Wood BL, Horton TM, Shannon KM, Teachey DT, Hermiston ML. Glucocorticoids paradoxically facilitate steroid resistance in T-cell acute lymphoblastic leukemias. J Clin Invest. 2020 Feb 3;130(2):863-876. doi: 10.1172/JCI130189. PMID: 31687977.

2019 and earlier

Huang BJ, Wandler A, Meyer L, Dail M, Daemen A, Sampath D, Li Q, Wang X, Wong JC, Nakitandwe J, Downing JR, Zhang J, Taylor B, Shannon K. Convergent Genetic Aberrations in Murine and Human T Lineage Acute Lymphoblastic Leukemias. PLoS Genet. 2019 Jun 14;15(6):e1008168. doi: 10.1371/journal.pgen.1008168. PMID: 31199785.

Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML. JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias. Leukemia. 2017 May 9. doi: 10.1038/leu.2017.136. PMID: 28484265.

Burgess MR, Hwang E, Mroue R, Bielski CM, Wandler AM, Huang BJ, Firestone AJ, Young A, LaCap J, Crocker L, Asthana S, Davis EM, Xu J, Akagi K, Le Beau MM, Li Q, Stokoe D, Sampath D, Taylor BS, Evangelista M, Shannon K. KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer. Cell. 2017 Feb 23;168(5):817-829.e15. doi: 10.1016/j.cell.2017.01.020. PMID: 28215705.

2024

Levinson A, Shannon K, Huang BJ (2024). Targeting Hyperactive Ras Signaling in Pediatric Cancer. In Kentsis A and Gutierrez A (Eds.), Developmental Oncology: Principles and Therapy of Cancers of Children and Young Adults, 1st Edition. In Press.

Lamble A and Huang BJ (2024). Chromosomal and Genomic Alterations in Pediatric AML. In D Tomizawa, D Reinhardt, and EA Kolb (Eds.), Acute Myeloid Leukemia in Children: Standard of Care and Future Perspectives, 1st Edition (pp 19-36). https://doi.org/10.1007/978-3-031-63366-9.

2023

Huang BJ and Shannon K. NFIA-ETO2, TP53 and erythroid leukemogenesis. Blood. 2023 May 4;141(18):2168-2170. doi: 10.1182/blood.2023019856. PMID: 37140954.